п»їProduct info: Anti Viral
Combivir (LAMIVUDINE + ZIDOVUDINE) is an anti-HIV medication. It is in a category of HIV medicines called nucleoside reverse transcriptase inhibitors (NRTIs). Combivir prevents HIV from altering the genetic material of healthy T-cells. This prevents the cells from producing new virus and decreases the amount of virus in the body. Combivir is marketed by GlaxoSmithKline. It was approved by the U.S. Food and Drug Administration (FDA) for use by people living with HIV in 1997.
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п»їCombivir
Generic Name: Lamivudine/Zidovudine (la-MIV-ue-deen/zye-DOE-vue-deen)
Brand Name: Combivir
One of the 2 active ingredients in Combivir , zidovudine, has been associated with certain blood disorders (eg, low white blood cell levels, severe anemia), especially in patients with advanced HIV disease, and muscle pain and inflammation, when it is used for long periods of time. High levels of lactic acid in the blood and severe liver problems, which may be life-threatening, have been reported with the use of Combivir .
Some patients with both HIV and hepatitis B infection who were taking lamivudine have developed severe worsening of their hepatitis B after they stopped taking lamivudine. Patients who have both HIV and hepatitis B infection and who stop using Combivir should have their liver function closely checked for at least several months after their last dose.
Combivir is used for:
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Treating HIV infection in combination with other medicines.
Combivir is an antiviral combination. Lamivudine and zidovudine are both nucleoside analogues that work together to slow the growth of HIV by blocking an enzyme needed by the virus to reproduce.
Do NOT use Combivir if:
you are allergic to any ingredient in Combivir
you are also taking stavudine, zalcitabine, or other medicines containing lamivudine or zidovudine
you have severe kidney problems, decreased liver function, abnormal liver function tests, or high levels of lactic acid in the blood (lactic acidosis)
Contact your doctor or health care provider right away if any of these apply to you.
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